Drug Information

Gilenya (fingolimod) FDA Approved Breakthrough Therapy

Gilenya was the first once-a-day pill approved to treat relapsing multiple sclerosis (MS). Approved for first-line use, Gilenya is a disease-modifying therapy (DMT) that offers freedom from injections, which may fit many patients’ lifestyles. Gilenya helps slow down the physical problems caused by RRMS and decreases the frequency of MS flare-ups (relapses).

Gilenya is the most prescribed oral once-daily DMT. In the US, approximately 73,000 patients have been exposed to Gilenya. Worldwide, Gilenya has been used to treat approximately 217,000 patients in both clinical trials and the post-marketing setting, with approximately 480,000 years of patient experience

Resources for MS Drug Therapies

"An Introduction to Disease Modifying Drugs" (DMD's)

Visit MS Society UK to learn more about DMD’s
“Disease modifying therapies (DMTs) are not a cure for MS, but they can reduce how many relapses someone has and how serious they are.”

Comprehensive List of MS Drugs, Dose and Use, and Interactions

Visit this Link to See a Comprehensive List of MS Drugs
“Medications are used in multiple sclerosis (MS) to modify the disease course, treat relapses — also called attacks or exacerbations — and manage symptoms. Along with the other essential components of comprehensive MS care, these medications help people manage their MS and enhance their comfort and quality of life. ” – National MS Society

Disease Modifying Therapies
  • The only drug currently approved for pediatric use is Gilenya. Use of other DMT’s under the age of 18 is considered “off-label”.
  • Not all drugs listed are available in all countries
  • Please consult your child’s physician with any questions regarding the use of DMT’s

Injectables

Injectables

Extavia
Betaseron
Avonex
Plegridy
Rebif
Copaxone
Glatopa

Oral

Oral
Gilenya
Tecfidera
Aubagio
*Imuran
*CellCept
 

Infusion

infusion

Tysabri
Lemtrada
Ocrevus
*Rituxan
*Cytoxan
*CellCept
Mitoxantrone

* “these drugs are off-label, use is not indicated for the treatment of MS”

Drugs Commonly Used for Acute Replapse Treatment

Steroids (Methylprednisolone
Prednisone
Acthar
Decadron
Dexamethasone
IVIg